The tumour suppressor p53 is now known to be an ancient transcription factor that had already evolved interaction sites with its partner protein MDM2 at the dawn of multi-cellular eukaryotic animal life.The billion-year life history of the p53-MDM2 axis has permitted significant time for the proteins to integrate into a distinct range of cellular p

Cauliflower mosaic virus (CaMV) gene VI protein (P6) is an important determinant of symptom expression.Differential display polymerase chain reaction (PCR) was used to identify changes in gene expression in Arabidopsis elicited by a P6 transgene that causes a symptomatic phenotype.We used slot blot hybridization to measure the abundance of mRNAs co

This study aimed at determining the quality parameters of the wafer formulated with the addition of grain spent (SG), resulting from the obtainment of whisky.In this sense, Gel Doccia wafers were formulated from chickpea flour, spent grain, wild garlic paste, golden flaxseed, and hemp seeds.These food products were analyzed in terms of texture, den

The purpose of the work is to study the influence of the control of the elastic and damping characteristics of the cushioning system based on the use of magnetorheological elastomers on the smoothness of the course of wheeled transport vehicles.The technique.The research used the methods of: magnetic field theory, the theory of vehicle suspension,

BackgroundThe mouse is increasingly used in biomedical research, notably in behavioral neurosciences for the development of tests or models of pain.Our goal was to provide the scientific community with an outstanding tool that allows the determination of psychophysical descriptors of a nociceptive reaction, which are inaccessible with conventional